Description
Protein A is a cell wall protein of Staphylococcus aureus, it has a variety of specific biological characteristics.
Due to its high affinity with the Fc part of certain immunoglobulins (especially IgG), it is widely used in the purification of biopharmaceuticals (such as antibodies, vaccines, etc.).
However, during the purification, protein A may leach from the purification column and result in contamination of the antibody drugs prepared.
Once the remaining protein A enters the human body, it will easily activate the immune response of the organism, and there is a safety risk, so there are strict regulations on the residual level of Protein A in antibody drug preparations.
Therefore, the detection of residual Protein A in antibody drugs purified from Protein A purification column is a key quality control step in the production process of antibody drug preparations.
The Universal Protein A ELISA Kit can detect protein A or unnatural protein A variants within 2 hours, it is high sensitive and easy to use.
Whether in upstream small-scale trials or downstream large-scale of antibody production processes, this kit can help you to accurate analysis of samples, monitor the protein A levels and ensure product quality